Mart de Jong
Quirine ten Bosch
Emergence of mosquito-borne diseases critically depends on the presence, abundance, and interplay between hosts, vectors, and pathogens. The Netherlands is an interesting region for mosquito-borne disease outbreak with its many travel connections, presence of water bodies, high density population areas, intensive farming and a variety of ecosystems. This leads to many potential interactions between different hosts, vectors, and pathogens, both established and newly imported ones. The risk of an outbreak is dependent on where, when, how frequently and between whom these interactions take place. Within the OH-PACT project, a lot of data will be collected on hosts, vectors, and pathogens. This project aims to bring these different data streams together to understand previous arbovirus outbreaks (R0, spatial spread, speed of transmission), predict the risk of future ones (importation and subsequent spread, R0, spatial and temporal patterns) and provide guidance on potential mitigation strategies (effect of interventions and sampling strategy).
Research questions / objectives
Epidemiological modelling: I will build transmission models using collected data to predict spread (R0), speed and final size of potential outbreaks
Virus (general): All my objectives focus on arboviruses.
West Nile virus: I will focus on WNV for obj 2 and 4. I will assess the risk of WNV emerging in NL.
Usutu Virus: I will focus on Usutu for obj 1 where I reconstruct outbreaks of the previous years in NL.
Japanese Encephalitis Virus: I might use JEV for obj 3 to look at the risk of it developing urban transmission cycles. I might also study JEV to assess the risk of it emerging in NL.
Mayaro Virus: I might use Mayaro virus for obj 3 to look at the risk of it developing urban transmission cycles. I might also study Mayaro to assess the risk of it emerging in NL.
Rift Valley Fever Virus: I might use RVFV for obj 3 to look at the risk of it developing urban transmission cycles. I might also study RVFV to assess the risk of it emerging in NL.
This project 'Preparing for vector-borne virus outbreaks in a changing world: a One Health Approach' (NWA. 1160.1S.210) is (partly) financed by the Dutch Research Council (NWO).
OHPACT is a NWA ORC project. More info can be found here