The Netherlands is particularly vulnerable to outbreaks of viral diseases transmitted by mosquitoes due to its water-dominated landscape, dense humans and livestock population and the expected establishment of new mosquito species such as Aedes albopictus. Separated and reaction-based research efforts into the numerous factors interplaying in the emergence of viral outbreaks, however results in disconnected research findings and critical factors unstudied. The One Health PACT is a research collaboration of experts in a wide variety of fields relevant for infectious disease outbreaks, ranging from ecological and climate modelling to medical entomology, virology and public health.
The One Health PACT project takes place within a multidisciplinary research field. The aim of our project is to extensively look into all aspects of preparedness of potential arboviral introduction and spread. To reach this goal, many partners from different fields are involved. Among those partners are the universities, where our PhD students and Post-doc are located. In addition to that, the NWO financed this project together with several co-financiers that all provide their expertise in different research fields. Lastly, there are national and international collaborating partners involved in the project by sharing data and knowledge with our researchers. An overview of all the partners is given below.
On the news page of our website you can find updates on our projects and news articles on exciting findings and events within our project.
A recent publication in Eurosurveillance describes the detection of Usutu RNA in six birds in Greater London. Although the presence of neutralising antibodies in birds had been shown before, this is the first time that the virus has been detected in birds in the United Kingdom. The recently documented infections are likely to be the result of autochthonous transmission via mosquitoes. The six infected birds (five blackbirds and one house sparrow) were sampled between 15 July and 26 August 2020.
On the 20th of November, the Dutch daily newspaper de Volkskrant published an article about the research conducted in the One Health PACT consortium.
In this article, Marion Koopmans, Sander Koenraadt and Maarten Hoek talk about climate change, vector competence and citizen science. You can read the full article (in Dutch) on the website.
Joyce van Bree (one of the One Health PACT, PhD candidates) has been awarded with the Rob Goldbach Virology MSc thesis prize 2020.
This prize is handed out every two years for the best master thesis delivered for examination at the Laboratory of Virology in Wageningen. Joyce fully deserves this prize based on an excellent thesis. She identified a number of antiviral mosquito proteins that bound to a highly-structured RNA molecule derived from the West Nile and ZIKA virus genome. This RNA structure is required for efficient transmission of these viruses by mosquitoes.